Lewis County EMS took a woman to St. Joseph's Hospital in Buckhannon after a single-vehicle crash on Route 33 Tuesday night.
It happened around 6:15 p.m., according to 911 officials.
The Lewis County Sheriff's Department said the woman was headed west when her Jeep went off the road and hit the guardrail. It said she was unconscious when first responders arrived.
No word on the woman's name or condition.
Fire departments from Weston, Jane Lew, and Buckhannon all responded to the scene.