--Update 8:06 p.m.--
The Taylor County Sheriff's Department said the accident occurred when one vehicle traveling westbound on Rt. 50 in Taylor County collided with another vehicle traveling eastbound.
The Department is still investigating the cause of the crash.
The Department confirmed that one of the vehicles did catch on fire shortly after the crash, but no one was in the vehicle when it happened.
The Harrison County 911 Center said a two-vehicle accident on Route 50 sent two people to Ruby Memorial Hospital Saturday evening. Three others were transported to United Hospital Center.
According to the 911 center, the accident happened near the Fourco Glass Company in Flemington around 4:00 p.m. on Saturday.
The Taylor County Sheriff's Department is investigating.
The Bridgeport Fire Department and Flemington Volunteer Fire Department were on scene Saturday.
Names and conditions are not being released at this time.
It is unclear at this time what caused the accident.